Molecular Details
DICL_CP_0307908
- (2R)-2-aminopentanedioic acid
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0307908
PubChem CID
Molecular Formula
C5H9NO4 Molecular Weight
147.13 g/mol
Synonyms/Alias
[D-glutamic acid; 6893-26-1; H-D-Glu-OH; (R)-2-aminopentanedioic acid; (2R)-2-aminopentanedioic acid; D-Glu; D-glutamate; Glutamic acid D-form; D-2-Aminopentanedioic acid; D-(-)-Glutamic acid; R-(-)-G...
InChI Key
WHUUTDBJXJRKMK-GSVOUGTGSA-N
InChI
InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
IUPAC Name
(2R)-2-aminopentanedioic acid
CAS Number
59-30-3
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
19 18 0 0 0 0 0 0 0 0999 V2000
0.2907 0.1467 -0.4327 C 0 0 0 0 0 0 0 0 0 0 0 0
0.9854 0.1107 0.9375 C 0 0 0 0 0 0 0 0 0 0 0 0
2.3718 0.662...
Experimental Data
Activity Data
Target Ion Channel
Glutamate receptor ionotropic subunit kainate 2
Uniprot Accession Number
Function
Antagonist
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
Ki: 3280 nM
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
Not specified
Temperature
4 °C
Test Method
Binding assay ([3H] Kainate)
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
10
Rotatable Bonds
4
logP
-0.7369
Complexity
32.481
TPSA (Ų)
100.62
H-Bond Donors
3
H-Bond Acceptors
3
Ring Count
0